ZIP Codes of Jessamine County, KY

Population & People
Population & People
Total Population
53,624
Household Income
Household Income
Median Income
$92,962
Housing
Housing
Total Housing Units
20,837
Business & Economy
Business & Economy
Total Businesses
1,328
Employment
Employment
Employment Rate
59.83%
Education
Education
Bachelor's Degree+
33.44%
Source: U.S. Census ACS 2024 5-Year Estimates · rolled up across the 4 ZIPs in this county.
Data Last Updated: June 1, 2026
ZIP Codes:4 ZIP Codes (2 Standard, 2 PO Box, 0 Unique) [See All]
Area Code:859
Timezone:Eastern (GMT -05:00)
Local Time:2:12:19 PM
Population:53,624 [See All]
FIPS:21113
CBSA:Lexington-Fayette, KY
Land Area:165 sq mi
Water Area:2 sq mi
Coordinates:37.8839, -84.6038
Quick Link:
https://www.zip-codes.com/county/ky-jessamine.asp
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Among Kentucky's 5 wealthiest counties
#3 statewide, average median income $92,962.

Standout ZIPs in this County


Most Populous
Nicholasville · 45,849 people
85.5% of county total
Highest Income
Keene· $130,625 median
1.4× county average
Largest Land Area
Nicholasville · 138.3 sq mi
Spans the most ground
Fastest Growth
Nicholasville · 10.9% (10-yr)
41,361 → 45,849 residents
Most Educated
Wilmore · 45.4% bachelor's+
2,054 of 4,529 adults 25+

Things worth knowing about Jessamine County


53,624 residents live across 4 ZIPs covering 165 sq mi, served by 3 distinct USPS-recognized cities.

Population moved from 48,997 to 53,624 from 2014 to 2024 — a +9.4% change. 2 ZIPs gained residents, 1 lost.

The county's wealthiest ZIP 40339 (Keene, $130,625 median) and poorest ZIP 40390 (Wilmore, $73,767) are 6.4 miles apart — a 1.8× income gap across local geography.

Median home values vary 2.3× across this county — from $115,300 in 40339 (Keene) to $268,100 in 40356 (Nicholasville).

Density varies across the county — from 281 people/sq mi in 40390 (Wilmore) to 331 in 40356 (Nicholasville).

Educational attainment ranges from 2.4% bachelor's+ in 40339 (Keene) to 45.4% in 40390 (Wilmore) — the breadth of educational profiles across the area.

Within Kentucky, this is the #18 most populous of 120 counties and ranks #3 for median household income with the #16 fastest decade growth .

Weighted by population, the typical household earns about $74,756 across the county — reflecting what a typical resident sees, not a simple ZIP average.

33.4% of adults age 25+ hold a bachelor's degree or higher (12,020 of 35,947 reporting).

2 Standard delivery, 2 PO Box only, 0 single-entity Unique ZIPs serve this county.

Stories about Jessamine County


Single-ZIP anchor

One ZIP holds the majority of this county's population — a sign of a county built around a single city or town.

Nicholasville

All ZIP Codes in Jessamine County


ZIPCityTypePopulationMedian IncomeArea (sq mi)10-yr Growth
40356NicholasvilleStandard45,849$74,495138.310.9%
40390WilmoreStandard7,429$73,76726.4-2.7%
40339KeenePO Box346$130,6250.0
40340NicholasvillePO Box0.0

Adjacent & Nearby Counties