ZIP Code 78221 in San Antonio, TX

Data Last Updated: November 1, 2025
City:San Antonio, Texas
County:Bexar County
Timezone:Central (GMT -06:00)
Local Time:8:01:37 PM
Population:39,779 [See All]
Area Codes:210 / 726
Classification:Standard [Normal Street Delivery]
Coordinates:29.2920, -98.4756
Land Area:36.311 sq mi
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Population & Demographics


ZIP Code 78221 has 39,779 residents and 12,976 households (average 3.06 persons per household). The median age is 34.5 years, slightly younger than the state (35.6) and younger than the nation (38.8). The gender split is 49.1% male and 50.9% female, which is about the same as the state male share (49.4%), making this a female-majority area. Largest groups are Hispanic or Latino (88.5%) and White (42.2%, much lower than the state average of 50.1% and well below the national average of 61.6%); Hispanic or Latino residents make up 88.5%, which is much higher than the national average (18.7%), and Other / Two or More Races share is much higher than the national average (8.4%).

Explore More:Population Over TimeBy Age & GenderBy RaceBy GenderNativity & Citizenship

Source: U.S. Census 2020 Demographics & Housing Characteristics (DHC) and U.S. Census 2011-2023 American Community Survey (ACS) 5-Year Estimates.
2020 Population:39,779Source: Census DHC
2023 ACS Population Estimate:41,580Source: Census ACS
2025 ZC Population Estimate:46,787Source: ZIP-Codes.com
Population Density:1,095.5 people per sq mile
Average Income:$63,114Source: Census ACS
Households:12,976Source: Census DHC
Average House Value:$157,500Source: Census ACS
Persons Per Household:3.06Source: Census DHC
Average Family Size:3.49Source: Census ACS

Population Over Time (with 2010 & 2020 Census Benchmarks)


Group20102011210220132014201520162017201820192020202120222023
Census ACS Population Estimate--36,03236,05737,08637,92337,74338,28940,24939,52341,18542,53541,96440,27241,580
Decennial Census35,990------------------39,779------
Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. DP05. DEMOGRAPHIC AND HOUSING ESTIMATES

Population by Age & Gender (Total, Male, Female)


Median Age: 34.5

Male Median Age: 32.9

Female Median Age: 35.9

Group< 55-910-1415-1920-2425-2930-3435-3940-4445-4950-5455-5960-6465-6970-7475-7980-8485+
Male1,3751,4241,7431,6131,4541,3771,2891,2681,1661,1691,1361,1611,034832571391286228
Female1,3441,4571,5351,5101,3531,3451,3401,3091,1851,2661,2331,2121,0751,008796574360360
Total2,7192,8813,2783,1232,8072,7222,6292,5772,3512,4352,3692,3732,1091,8401,367965646588
Source: U.S. Census Bureau (2020) Demographics & Housing Characteristics (DHC)

Population by Race


White:16,80526.85%
Black:5780.92%
Hispanic:*35,20556.26%
Asian:1960.31%
American Indian:5690.91%
Hawaiian:140.02%
Other:9,21414.72%
Total:62,581100%
Source: U.S. Census Bureau (2020) Demographics & Housing Characteristics (DHC)
* NOTE: Hispanic or Latino is an ethnicity, not a race. This means individuals who identify as Hispanic will also be included in one of the race categories (such as White or Black). As a result, the totals shown here may exceed 100% when Hispanic is displayed alongside racial groups.

Gender Breakdown


GenderCount%Median Age
Males:19,51749.06%32.9 years
Females:20,26250.94%35.9 years
Total:39,779100%34.5 years
Source: U.S. Census Bureau (2020) Demographics & Housing Characteristics (DHC)

Nativity & Citizenship


Native, born in the United States:34,56083.12%
Native, born in PR, Island Areas, or abroad:5171.24%
Foreign born, naturalized U.S. citizen:2,2815.49%
Foreign born, not a U.S. citizen:4,22215.64%
Total Population:41,580100%
Total Native Population:35,07784.36%
Total Foreign-born Population:6,50315.64%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP02. SELECTED SOCIAL CHARACTERISTICS
Note: Nativity and Citizenship derived from American Community Survey (ACS) 5-year estimates. Total Population listed here will not match official ZIP Code population totals, which are based on the Decennial Census.

Income & Employment


In 2023, the Median household income is $63,114, which is well under the national median ($78,538), is up $24,385 (63.0%) since 2011 and above its 2019 pre-pandemic level by $19,677. Family households earn a median of $71,240 versus $27,662 for nonfamily households (a difference of $43,578). By gender, male median income is $41,895 and female is $38,570, which is well under the national female median ($53,445), with a current gap of $3,325 that has narrowed from 2011 to 2023. The labor-force participation rate is 63.0%, which is modestly under the state rate (65.3%). The unemployment rate is 5.8%, which is edges higher than the state rate (5.1%). The largest occupation group is Management (23.2%).

Explore More:Income Over TimeHousehold IncomeEmployment StatusBy Occupation

Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. Using data from Tables DP02, DP03, DP04 and DP05.

Median Income Over Time (Household, Family, Nonfamily, Male, Female)


Income Type2011201220132014201520162017201820192020202120222023
Median Household Income$38,729$38,555$38,036$38,057$36,977$36,474$39,531$40,029$43,437$45,950$51,115$57,209$63,114
Median Family Income$43,281$42,160$42,131$43,132$42,416$41,926$44,082$45,844$49,219$54,014$60,087$65,827$71,240
Median NonFamily Income$22,215$21,007$21,790$20,179$19,134$19,938$21,335$22,183$22,662$23,519$25,693$28,730$27,662
Median Male Income$30,543$30,328$30,605$31,490$30,799$30,727$32,296$34,209$33,775$34,313$36,516$40,221$41,895
Median Female Income$25,674$25,395$26,119$26,127$25,511$26,816$27,375$28,800$29,834$31,123$33,503$36,138$38,570
Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. DP03. SELECTED ECONOMIC CHARACTERISTICS

Average Household Income


Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP03. SELECTED ECONOMIC CHARACTERISTICS

Employment Status


Employed:19,01359.23%
Unemployed:1,1783.67%
Not In Labor Force:11,91037.10%
Total:32,101100%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP03. SELECTED ECONOMIC CHARACTERISTICS

Employment by Occupation (Civilian Employed Population, 16 and Over)


Management, business, science, and arts:4,41423.22%
Service:4,13621.75%
Sales and Office:4,33222.78%
Natural resources, construction, and maintenance:2,73914.41%
Production, transportation, and material moving:3,39217.84%
Total Civilian Employed Population:19,013100%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP03. SELECTED ECONOMIC CHARACTERISTICS.

Housing & Affordability


In 2023, the median home value is $157,500, which is far less than the national median ($303,400), is up $80,600 (104.81%) since 2011 and above its 2019 pre-pandemic level by $69,800. The median gross rent is $1,147, which is far less than the national median ($1,348), is up $428 (59.53%) since 2011 and above its 2019 pre-pandemic level by $300. Of occupied housing, owners make up 69.80% (50.94% with a mortgage, 49.06% free-and-clear) and renters 30.20% - making this ZIP Code more home ownership than the state and under national rental averages. The vacancy rate is 12.08%, which is far higher than the state rate (9.62%).

Explore More:Compare Home ValueHome Value Over TimeRent & Over TimeHousing Occupancy

Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. Using data from Table DP03, SELECTED ECONOMIC CHARACTERISTICS.

Median Home Value (Comparison)


Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP04. SELECTED HOUSING CHARACTERISTICS

Median Home Value Over Time


Group2011210220132014201520162017201820192020202120222023
Median Home Value$76,900$79,700$81,200$80,800$79,400$78,800$79,300$82,400$87,700$92,700$107,600$138,900$157,500
Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. DP04. SELECTED HOUSING CHARACTERISTICS

Gross Rent Paid


Less than $500:2105.29%
$500 to $999:1,20930.48%
$1,000 to $1,499:1,62240.89%
$1,500 to $1,999:3799.55%
$2,000 to $2,499:2797.03%
$2,500 to $2,999:601.51%
$3,000 or more:180.45%
No Rent:1904.79%
Total:3,967100%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP04. SELECTED HOUSING CHARACTERISTICS

Median Gross Rent Over Time


Group2011210220132014201520162017201820192020202120222023
Median Rent$719$727$736$754$757$770$793$813$847$889$969$1,043$1,147
Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. DP04. SELECTED HOUSING CHARACTERISTICS

Housing Occupancy


Owner Occupied (with mortgage):4,67035.56%
Owner Occupied (free and clear, no mortgage):4,49734.24%
Renter Occupied:3,96730.20%
Total Occupied Housing Units:13,134100%

Occupied Housing Units:13,13487.92%
Vacant Housing Units (not graphed):1,80512.08%
Total Housing Units:14,939100%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP04. SELECTED HOUSING CHARACTERISTICS

Housing Type (Single-Family, Multi-Family, Other)


Single-Family Units:12,07580.83%
Multi-Family Units:2,24715.04%
Other Units:6174.13%
Total Housing Units:14,939100%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP04. SELECTED HOUSING CHARACTERISTICS

Education, Health & Community


In 2023, 11.90% of adults (25+) have a bachelor's degree or higher, which is far lower than the national rate (35.00%). High school or higher is 74.00%, which is far lower than the national rate (89.40%). The uninsured rate is 23.40%, which is far higher than the national rate (8.60%). Private coverage is 47.40%, which is falls below the national rate (67.30%). The share of people in poverty is 15.40%, which is far higher than the national rate (8.70%), down 2.50 percentage points since 2011 and below its 2019 pre-pandemic level by 3.00 percentage points. This suggests a positive shift in the local economic and social landscape - higher incomes, steadier consumer demand, and a strengthening tax base. Among residents ages 3+, the largest enrollment group is elementary (40.56%). College enrollment is 22.58%, which is falls below the national rate (26.70%), indicating the community may be more oriented toward vocational/trade or direct-to-workforce opportunities.

Explore More:Educational AttainmentHealth InsurancePoverty Over TimeSchool Enrollment

Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. Using data from Tables DP02 and DP03.

Educational Attainment of Adults (25 and Older)


Less than 9th grade:3,37112.88%
9th to 12th grade, no diploma:3,44713.17%
High school graduate (includes equivalency):9,35435.74%
Some college, no degree:5,00719.13%
Associate's degree:1,8807.18%
Bachelor's degree:2,0407.79%
Graduate or professional degree:1,0764.11%
Total:26,175100%
High school or higher:19,35773.95%
Bachelor's degree or higher:3,11611.90%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP02. SELECTED SOCIAL CHARACTERISTICS

Health Insurance Coverage by Type (Private, Public, Uninsured)


Private Insurance:19,63144.42%
Public Insurance:14,88533.68%
No Insurance:9,67921.90%
Total:44,195100%
Has Health Insurance:34,51678.10%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP03. SELECTED ECONOMIC CHARACTERISTICS

Percentage of People in Poverty Over Time (2011-2023)


Group2011210220132014201520162017201820192020202120222023
% of People in Poverty17.9%20.4%21.0%21.9%20.7%21.3%19.7%20.0%18.4%18.9%17.6%16.5%15.4%
Source: U.S. Census 2011-2023 American Community Survey 5-Year Estimates. DP03. SELECTED ECONOMIC CHARACTERISTICS

Note: Counts of Families & People in poverty are not published at the ZIP Code level due to small sample sizes. Percentages shown are survey estimates from the American Community Survey (ACS). They may differ from official poverty statistics. The U.S. Census Bureau defines poverty status by comparing a family's or individual's total income with federal poverty thresholds that vary by family size and composition.

School Enrollment by Education Level (Ages 3 and Older)


Nursery School, Preschool:4564.04%
Kindergarten:7686.80%
Elementary school (grades 1-8):4,58440.56%
High school (grades 9-12):2,94126.02%
College or graduate school:2,55222.58%
Total:11,301100%
Early Childhood:1,22410.83%
K-12 (Primary & Secondary School):8,29373.38%
Source: U.S. Census 2019-2023 American Community Survey 5-Year Estimates. Table DP02. SELECTED SOCIAL CHARACTERISTICS

Business & Employment Statistics


ZIP Code 78221 supports both business and residential activity. According to the Business Census (2023), there are 513 business establishments, employing about 27,803 people with an annual payroll of $1,957,676,000. USPS data shows 15,290 residential mailboxes and 894 business mailboxes, reflecting local delivery coverage.

# Residential Mailboxes:15,290Source: USPS
# Business Mailboxes:894Source: USPS
Total Delivery Receptacles:17,825Source: USPS
Single Family Delivery Units:9,794Source: USPS
Multi Family Delivery Units:1,781Source: USPS
# of Businesses:513Source: CBP
1st Quarter Payroll:$399,305,000Source: CBP
Annual Payroll:$1,957,676,000Source: CBP
# of Employees:27,803Source: CBP

Geography, Land Area, & Statistical Classifications


ZIP Code 78221 is located in Bexar County, Texas, within the San Antonio-New Braunfels, TX Metropolitan Statistical Area (CBSA 41700) and Texas's 20th, 23rd, and 28th Congressional Districts. This Metro area has a population of 2,612,802 people, about 1.52% of whom live in ZIP Code 78221. It covers 36.311 sq mi of land and a water area of 1.835 sq mi.

CBSA Name:San Antonio-New Braunfels, TXSource: Census
CBSA Number:41700Source: Census
CBSA Type:MetroSource: Census
CBSA Division:--Source: Census
CBSA Population:2,612,802Source: Census
MSA:San Antonio, TX MSASource: Census
Land Area:36.311 sq miSource: Census
Water Area:1.835 sq miSource: Census
Congressional District:20,23,28Source: USPS
Congressional Land Area:199.68, 58059.18, 9378.53 sq miSource: Census
PMSA:--Source: Census
Intro Date:< 2004-10Source: ZIP-Codes.com
Place FIPS Code:4865000Source: Census
Place Name:San Antonio city; TexasSource: Census

Adjacent & Nearby ZIP Codes


78222 | | 78220

Schools in ZIP Code 78221


ZIP Code 78221 is part of 2 school districts, including: Harlandale Independent School District (Grades PK thru 12) and Southside Independent School District (Grades Pre-Kindergarten thru 12th). There are 21 public schools and 1 private school(s) in this ZIP Code. It also has 6 colleges, universities or post secondary education institutions nearby which would be a short commute to.

Bellaire El 142 E Amber Pl
San Antonio, TX 78221
District: Harlandale Independent School District
Carroll Bell El 519 W Harding
San Antonio, TX 78221
District: Harlandale Independent School District
Gillette El 625 Gillette Blvd
San Antonio, TX 78221
District: Harlandale Independent School District
H W Schulze El 9131 Yett Blvd
San Antonio, TX 78221
District: Harlandale Independent School District
Kingsborough Middle 422 Ashley Rd
San Antonio, TX 78221
District: Harlandale Independent School District
Mccollum H S 500 W Formosa Blvd
San Antonio, TX 78221
District: Harlandale Independent School District
Rayburn El 635 Rayburn Dr
San Antonio, TX 78221
District: Harlandale Independent School District
Jewel C Wietzel Center 9131 Yett Bldg 4
San Antonio, TX 78221
District: Harlandale Independent School District
Terrell Wells Middle 422 W Hutchins Pl
San Antonio, TX 78221
District: Harlandale Independent School District
Vestal El 1102 Cantrell Dr
San Antonio, TX 78221
District: Harlandale Independent School District
Frank M Tejeda Academy 12121 S E Loop 410
San Antonio, TX 78221
District: Harlandale Independent School District
Tejeda Junior Academy 12121 Se Loop 410
San Antonio, TX 78221
District: Harlandale Independent School District
Southside H S 19190 US 281 S 2
San Antonio, TX 78221
District: Southside Independent School District
W M Pearce Pri 19190 Hwy 281 S 3
San Antonio, TX 78221
District: Southside Independent School District
Bexar Co J J A E P 1460 Martinez Losoya Rd
San Antonio, TX 78221
District: Southside Independent School District
Julian C Gallardo El 1300 Del Lago Rd
San Antonio, TX 78221
District: Southside Independent School District
Colonel Menchaca Early Childhood Center 16180 S US Hwy 281
San Antonio, TX 78221
District: Southside Independent School District
Losoya Middle 1610 Martinez Losoya Rd
San Antonio, TX 78221
District: Southside Independent School District
Trinity Alternative Education 1460 Martinez Losoya Rd
San Antonio, TX 78221
District: Southside Independent School District
Idea South Flores College Preparatory 6919 S Flores
San Antonio, TX 78221
Idea South Flores Academy 6919 S Flores
San Antonio, TX 78221
Victory Learning Center 660 Sw Military Dr Ste T
San Antonio, TX 78221
District: Private School

Colleges & Post Secondary Schools near ZIP Code 78221


Texas A&M University-San Antonio One University Way
San Antonio, TX 78224
Type: Post Secondary
Ucas University Of Cosmetology Arts & Sciences 910 Southeast Military, Suite 100
San Antonio, TX 78214
Type: Post Secondary
Miller-Motte College-Stvt-San Antonio 734 Se Military
San Antonio, TX 78216
Type: Post Secondary
Southern Careers Institute-San Antonio 238 Sw Military Drive, Suite 101
San Antonio, TX 78221
Type: Post Secondary
Palo Alto College 1400 W Villaret Blvd
San Antonio, TX 78224-2499
Type: Post Secondary
Southwest School Of Business And Technical Careers-San Antonio 229 Sw Military Drive
San Antonio, TX 78221-0138
Type: Post Secondary

Sources & References


Our sources include trusted federal and licensed data from the United States Postal Service, U.S. Census Bureau, U.S. Geological Survey, Centers for Medicare & Medicaid Services, and the National Center for Education Statistics, along with proprietary datasets created by ZIP-Codes.com. Data last updated on November 1, 2025.

  1. U.S. Postal Service [Last Updated: 11/1/2025], https://www.usps.com
  2. ZIP-Codes.com Proprietary Data Enhancements [Updated: 11/1/2025], https://www.zip-codes.com
  3. U.S. Census [Updated: Varies], https://www.census.gov
    • U.S. Census Office of Management and Budget [Updated: As Released]
    • U.S. Census 2020 Demographic & Housing Characteristics (DHC) [Decennial] [Updated: 5/25/2023]
    • U.S. Census 2011-2023 American Community Survey 5-year estimates (ACS) [Annually] [Updated: Annually, As Released]
    • U.S. Census Business Patterns (CBD) [Annually] [Updated: Annually, As Released]
    • U.S. Census American National Standards Institute (ANSI) [Updated: As Released]
  4. U.S. Geological Survey [Updated: Varies], https://www.usgs.gov
  5. Centers for Medicare & Medicaid Services [Updated: Annually, As Released], https://www.cms.gov
  6. National Center for Education Statistics [Updated: 11/1/2025], https://nces.ed.gov