ZIP Code 13221 in Syracuse, NY

Data Last Updated: February 1, 2026
City:Syracuse, New York
Names to Avoid:
Syr
County:Onondaga County
Timezone:Eastern (GMT -05:00)
Local Time:8:51:35 PM
Population:No Population Data
Area Codes:315 / 680
Classification:PO Box
Coordinates:43.0499, -76.1506
Quick Link:
https://www.zip-codes.com/zip-code/13221/zip-code-13221.asp

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13221 - Syracuse, NY

ZIP Code 13221, Syracuse

Small Town Unique ZIP No Census Data
LocationOnondaga County, NY
Area0 sq mi Single Point
PO Boxes0 No PO Boxes
Also Known AsSyr
ZIP CreatedBefore Oct 2004
Enclosed InZIP Code 13220
Key Facts
  • This is a PO Box only ZIP code serving the Syracuse area, with no street delivery routes within the zone itself.
  • The facility serves 43 businesses through 28 distinct PO Box ZIP+4 records.
  • Street delivery for this area is provided through neighboring ZIP code 13220, which encloses this postal service area.
  • The facility is geographically positioned within the Syracuse metropolitan area, with city delivery infrastructure available through adjacent zones.
  • Nearby neighborhoods include Mattydale, Lyncourt, Northside, Galeville, and Lakefront, all within 3.1 miles of the facility.

Postal Services

The facility maintains 28 PO Box ZIP+4 records serving 43 businesses. It's located at coordinates 43.049900, -76.150600, functioning as a complementary service point within Syracuse's broader postal infrastructure. Nearby neighborhoods include Mattydale (1.2 miles), Lyncourt (2.3 miles), and Northside (2.8 miles).

Street Name Patterns

No street delivery routes exist within ZIP 13221. This is a pure PO Box facility serving business customers in the Syracuse area.

Nearby Areas

Mattydale Lyncourt Northside Galeville Lakefront

Business & Employment Statistics


ZIP Code 13221 supports both business and residential activity. According to the Business Census (2024), there are 7 business establishments, employing about 1,370 people with an annual payroll of $148,235,000.

# Residential Mailboxes:0Source: USPS
# Business Mailboxes:0Source: USPS
Total Delivery Receptacles:41Source: USPS
Single Family Delivery Units:0Source: USPS
Multi Family Delivery Units:0Source: USPS
# of Businesses:7Source: CBP
1st Quarter Payroll:$49,532,000Source: CBP
Annual Payroll:$148,235,000Source: CBP
# of Employees:1,370Source: CBP

Geography, Land Area, & Statistical Classifications


ZIP Code 13221 is located in Onondaga County, New York, within the Syracuse, NY Metropolitan Statistical Area (CBSA 45060) and New York's 22nd Congressional District. This Metro area has a population of 662,577 people, about 0.00% of whom live in ZIP Code 13221. It covers 0 sq mi of land and a water area of 0 sq mi.

CBSA Name:Syracuse, NYSource: Census
CBSA Number:45060Source: Census
CBSA Type:MetroSource: Census
CBSA Division:--Source: Census
CBSA Population:662,577Source: Census
MSA:Syracuse, NY MSASource: Census
Land Area:--Source: Census
Water Area:--Source: Census
Congressional District:22Source: USPS
Congressional Land Area:5077.45 sq miSource: Census
PMSA:--Source: Census
Intro Date:< 2004-10Source: ZIP-Codes.com
Place FIPS Code:3673000Source: Census
Place Name:Syracuse city; New YorkSource: Census

Adjacent & Nearby ZIP Codes


13224 | | 13220

Schools in ZIP Code 13221


We could not locate which school district 13221 belongs to, but we will update this once new district data is released. There are no public schools nor private schools with a mailing address in this ZIP Code. Listing Nearby schools instead. It also has 6 colleges, universities or post secondary education institutions nearby which would be a short commute to.

Onondaga Cnty Sheriff's Dept 555 So State St
Syracuse, NY 13202
District: Syracuse City School DistrictNearby
Institute Of Technology At Syracuse Central 258 E Adams St
Syracuse, NY 13202
District: Syracuse City School DistrictNearby
Hutchings Child & Youth Services 430 Irving Ave
Syracuse, NY 13210
District: UnknownNearby
Seymour Dual Language Academy 108 Shonnard St
Syracuse, NY 13204
District: Syracuse City School DistrictNearby
Syracuse Stem At Blodgett 312 Oswego St
Syracuse, NY 13204
District: Syracuse City School DistrictNearby
Cathedral Academy At Pompei 923 N Mcbride St
Syracuse, NY 13208
District: Private SchoolNearby
All Saints Elementary Of Tipperary Hill 112 S Wilbur Ave
Syracuse, NY 13204
District: Private SchoolNearby
Most Holy Rosary School 1031 Bellevue Ave
Syracuse, NY 13207
District: Private SchoolNearby

Colleges & Post Secondary Schools near ZIP Code 13221


St. Joseph's College Of Nursing 206 Prospect Ave
Syracuse, NY 13203
Type: Post Secondary
Upstate Medical University 750 E Adams St
Syracuse, NY 13210
Type: Post Secondary
Bryant & Stratton College-Syracuse 953 James St
Syracuse, NY 13203-2502
Type: Post Secondary
Suny College Of Environmental Science And Forestry One Forestry Dr.
Syracuse, NY 13210
Type: Post Secondary
Syracuse University 900 South Crouse Ave.
Syracuse, NY 13244
Type: Post Secondary
Le Moyne College 1419 Salt Springs Rd
Syracuse, NY 13214-1301
Type: Post Secondary

Sources & References


Our sources include trusted federal and licensed data from the United States Postal Service, U.S. Census Bureau, U.S. Geological Survey, Centers for Medicare & Medicaid Services, and the National Center for Education Statistics, along with proprietary datasets created by ZIP-Codes.com. Data last updated on February 1, 2026.

  1. U.S. Postal Service [Last Updated: 2/1/2026], https://www.usps.com
  2. ZIP-Codes.com Proprietary Data Enhancements [Updated: 2/1/2026], https://www.zip-codes.com
  3. U.S. Census [Updated: Varies], https://www.census.gov
    • U.S. Census Office of Management and Budget [Updated: As Released]
    • U.S. Census 2020 Demographic & Housing Characteristics (DHC) [Decennial] [Updated: 5/25/2023]
    • U.S. Census 2011-2024 American Community Survey 5-year estimates (ACS) [Annually] [Updated: Annually, As Released]
    • U.S. Census Business Patterns (CBD) [Annually] [Updated: Annually, As Released]
    • U.S. Census American National Standards Institute (ANSI) [Updated: As Released]
  4. U.S. Geological Survey [Updated: Varies], https://www.usgs.gov
  5. Centers for Medicare & Medicaid Services [Updated: Annually, As Released], https://www.cms.gov
  6. National Center for Education Statistics [Updated: 2/1/2026], https://nces.ed.gov