ZIP Codes of Cherokee County, SC

Population & People
Population & People
Total Population
51,180
Household Income
Household Income
Median Income
$50,619
Housing
Housing
Total Housing Units
22,520
Business & Economy
Business & Economy
Total Businesses
887
Employment
Employment
Employment Rate
52.73%
Education
Education
Bachelor's Degree+
18.27%
Source: U.S. Census ACS 2024 5-Year Estimates · rolled up across the 4 ZIPs in this county.
Data Last Updated: June 1, 2026
ZIP Codes:4 ZIP Codes (3 Standard, 1 PO Box, 0 Unique) [See All]
Area Codes:821 / 864
Timezone:Eastern (GMT -05:00)
Local Time:2:13:39 PM
Population:51,180 [See All]
FIPS:45021
CBSA:Gaffney, SC
Land Area:358 sq mi
Water Area:4 sq mi
Coordinates:35.0638, -81.6121
Quick Link:
https://www.zip-codes.com/county/sc-cherokee.asp
Need Cherokee data in your app? Look up ZIP, county, and city data with a single API call.
Try Free
South Carolina's #24 most populous county
51,180 residents across 4 ZIPs — #24 of 46 South Carolina counties.

Standout ZIPs in this County


Most Populous
Gaffney · 20,763 people
40.6% of county total
Highest Income
Gaffney · $58,029 median
1.1× county average
Largest Land Area
Gaffney · 164.5 sq mi
Spans the most ground
Fastest Growth
Gaffney · 7.0% (10-yr)
19,293 → 20,647 residents
Most Educated
Gaffney · 26.9% bachelor's+
3,776 of 14,063 adults 25+

Things worth knowing about Cherokee County


51,180 residents live across 4 ZIPs covering 358 sq mi, served by 2 distinct USPS-recognized cities.

Population moved from 50,305 to 51,180 from 2014 to 2024 — a +1.7% change. 2 ZIPs gained residents, 1 lost.

The county's wealthiest ZIP 29341 (Gaffney, $58,029 median) and poorest ZIP 29340 (Gaffney, $44,123) are 10.5 miles apart — a 1.3× income gap across local geography.

Median home values vary 1.7× across this county — from $108,800 in 29340 (Gaffney) to $188,900 in 29341 (Gaffney).

Density varies across the county — from 99 people/sq mi in 29702 (Blacksburg) to 219 in 29341 (Gaffney).

Educational attainment ranges from 11.2% bachelor's+ in 29340 (Gaffney) to 26.9% in 29341 (Gaffney) — the breadth of educational profiles across the area.

Within South Carolina, this is the #24 most populous of 46 counties and ranks #33 for median household income .

Weighted by population, the typical household earns about $50,799 across the county — reflecting what a typical resident sees, not a simple ZIP average.

18.3% of adults age 25+ hold a bachelor's degree or higher (6,327 of 34,626 reporting). The most-educated ZIPs cluster around Gaffney.

3 Standard delivery, 1 PO Box only, 0 single-entity Unique ZIPs serve this county.

All ZIP Codes in Cherokee County


ZIPCityTypePopulationMedian IncomeArea (sq mi)10-yr Growth
29340GaffneyStandard20,763$44,123164.5-3.2%
29341GaffneyStandard20,647$58,02994.37.0%
29702BlacksburgStandard9,770$49,70599.02.1%
29342GaffneyPO Box0.0

Adjacent & Nearby Counties