ZIP Codes of Saint Charles County, MO

Population & People
Population & People
Total Population
416,486
Household Income
Household Income
Median Income
$111,071
Housing
Housing
Total Housing Units
168,100
Business & Economy
Business & Economy
Total Businesses
8,966
Employment
Employment
Employment Rate
67.22%
Education
Education
Bachelor's Degree+
42.63%
Source: U.S. Census ACS 2024 5-Year Estimates · rolled up across the 17 ZIPs in this county.
Data Last Updated: June 1, 2026
ZIP Codes:17 ZIP Codes (13 Standard, 4 PO Box, 0 Unique) [See All]
Area Codes:314 / 557 / 636
Timezone:Central (GMT -06:00)
Local Time:2:12:45 PM
Population:416,486 [See All]
FIPS:29183
CBSA:St. Louis, MO-IL
Land Area:599 sq mi
Water Area:32 sq mi
Coordinates:38.7766, -90.6768
Quick Link:
https://www.zip-codes.com/county/mo-saint-charles.asp
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Missouri's highest-income county
Average median income $111,071 — the highest of 116 counties.
Top 3 most populous in Missouri
#3 of 116 counties in Missouri, with 416,486 residents.
Among Missouri's 5 densest counties
695 people per square mile (#4 statewide).
Among Missouri's 5 most-educated counties
42.6% with bachelor's+ (#4 statewide).

Standout ZIPs in this County


Most Populous
Saint Peters · 74,962 people
18.0% of county total
Highest Income
Defiance · $170,598 median
1.5× county average
Largest Land Area
Saint Charles · 105.4 sq mi
Spans the most ground
Fastest Growth
Foristell · 56.3% (10-yr)
6,649 → 10,394 residents
Most Educated
Defiance · 54.1% bachelor's+
1,353 of 2,502 adults 25+

Things worth knowing about Saint Charles County


416,486 residents live across 17 ZIPs covering 599 sq mi, served by 13 distinct USPS-recognized cities.

Population moved from 371,402 to 416,435 from 2014 to 2024 — a +12.1% change. 10 ZIPs gained residents, 3 lost.

The county's wealthiest ZIP 63341 (Defiance, $170,598 median) and poorest ZIP 63301 (Saint Charles, $85,308) are 21.4 miles apart — a 2.0× income gap across local geography.

Median home values vary 2.3× across this county — from $267,600 in 63301 (Saint Charles) to $606,800 in 63341 (Defiance).

Density varies 110× across the county — from 27 people/sq mi in 63332 (Augusta) to 2,903 in 63303 (Saint Charles).

Educational attainment ranges from 32.7% bachelor's+ in 63332 (Augusta) to 54.1% in 63341 (Defiance) — the breadth of educational profiles across the area.

Within Missouri, this is the #3 most populous of 116 counties and ranks #1 for median household income with the #9 fastest decade growth .

Weighted by population, the typical household earns about $107,064 across the county — reflecting what a typical resident sees, not a simple ZIP average.

42.6% of adults age 25+ hold a bachelor's degree or higher (123,222 of 289,063 reporting).

13 Standard delivery, 4 PO Box only, 0 single-entity Unique ZIPs serve this county.

All ZIP Codes in Saint Charles County


ZIPCityTypePopulationMedian IncomeArea (sq mi)10-yr Growth
63376Saint PetersStandard74,962$96,39333.93.4%
63366O FallonStandard54,769$100,62168.313.5%
63301Saint CharlesStandard52,667$85,308105.46.0%
63385WentzvilleStandard51,330$112,19970.239.6%
63368O FallonStandard46,966$124,29716.97.1%
63303Saint CharlesStandard46,089$99,13815.9-1.4%
63304Saint CharlesStandard43,195$114,44243.18.4%
63367Lake Saint LouisStandard29,725$137,64813.640.3%
63348ForistellStandard10,394$115,66155.056.3%
63341DefianceStandard3,515$170,59856.1-0.2%
63332AugustaStandard1,651$146,14662.321.3%
63373Portage Des SiouxStandard690$88,75019.151.3%
63386West AltonStandard482$110,25039.2-19.8%
63365New MellePO Box51$53,5420.0
63338CottlevillePO Box0.0
63302Saint CharlesPO Box0.0
63346FlinthillPO Box0.0

Adjacent & Nearby Counties