| ZIP Codes: | 6 ZIP Codes (3 Standard, 3 PO Box, 0 Unique) [See All] |
| Area Codes: | 235 / 573 |
| Timezone: | Central (GMT -06:00) |
| Local Time: | 11:54:02 PM |
| Population: | 12,435 [See All] |
| FIPS: | 29133 |
| CBSA: | Sikeston, MO |
| Land Area: | 515 sq mi |
| Water Area: | 18 sq mi |
| Coordinates: | 36.8365, -89.3008 |
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12,435 residents live across 6 ZIPs covering 515 sq mi, served by 6 distinct USPS-recognized cities.
Population moved from 14,711 to 12,435 from 2014 to 2024 — a -15.5% change. 1 ZIPs gained residents, 4 lost.
The county's wealthiest ZIP 63823 (Bertrand, $62,656 median) and poorest ZIP 63882 (Wyatt, $30,227) are 13.1 miles apart — a 2.1× income gap across local geography.
Median home values vary 2.0× across this county — from $57,100 in 63882 (Wyatt) to $114,000 in 63834 (Charleston).
Density varies 55× across the county — from 19 people/sq mi in 63834 (Charleston) to 1,046 in 63882 (Wyatt).
Educational attainment ranges from 2.3% bachelor's+ in 63820 (Anniston) to 18.3% in 63823 (Bertrand) — the breadth of educational profiles across the area.
Within Missouri, this is the #76 most populous of 116 counties and ranks #106 for median household income .
Weighted by population, the typical household earns about $47,818 across the county — reflecting what a typical resident sees, not a simple ZIP average.
14.4% of adults age 25+ hold a bachelor's degree or higher (1,227 of 8,502 reporting).
3 Standard delivery, 3 PO Box only, 0 single-entity Unique ZIPs serve this county.
A frontier county — vast land area with only a few residents per square mile. Daily life looks very different here than in the country's denser counties.
Mississippi County lost 15.5% of residents between 2014 and 2024. ZIPs that shed the largest share: