ZIP Codes of Madison County, MO

Population & People
Population & People
Total Population
13,193
Household Income
Household Income
Median Income
$58,108
Housing
Housing
Total Housing Units
6,052
Business & Economy
Business & Economy
Total Businesses
236
Employment
Employment
Employment Rate
54.55%
Education
Education
Bachelor's Degree+
16.31%
Source: U.S. Census ACS 2024 5-Year Estimates · rolled up across the 2 ZIPs in this county.
Data Last Updated: June 1, 2026
ZIP Codes:2 ZIP Codes (2 Standard, 0 PO Box, 0 Unique) [See All]
Area Codes:235 / 573
Timezone:Central (GMT -06:00)
Local Time:2:12:44 PM
Population:13,193 [See All]
FIPS:29123
Land Area:532 sq mi
Water Area:3 sq mi
Coordinates:37.4626, -90.2838
Quick Link:
https://www.zip-codes.com/county/mo-madison.asp
Need Madison data in your app? Look up ZIP, county, and city data with a single API call.
Try Free
Missouri's #71 most populous county
13,193 residents across 2 ZIPs — #71 of 116 Missouri counties.

Standout ZIPs in this County


Most Populous
Fredericktown · 11,554 people
87.6% of county total
Highest Income
Marquand · $61,469 median
1.1× county average
Largest Land Area
Fredericktown · 379.1 sq mi
Spans the most ground
Fastest Growth
Marquand · 6.8% (10-yr)
1,535 → 1,639 residents
Most Educated
Fredericktown · 17.5% bachelor's+
1,383 of 7,918 adults 25+

Things worth knowing about Madison County


13,193 residents live across 2 ZIPs covering 532 sq mi, served by 2 distinct USPS-recognized cities.

Population moved from 12,923 to 13,193 from 2014 to 2024 — a +2.1% change. 2 ZIPs gained residents, 0 lost.

The county's wealthiest ZIP 63655 (Marquand, $61,469 median) and poorest ZIP 63645 (Fredericktown, $54,747) are 11.7 miles apart — a 1.1× income gap across local geography.

Median home values vary 1.1× across this county — from $157,500 in 63645 (Fredericktown) to $175,600 in 63655 (Marquand).

Density varies across the county — from 11 people/sq mi in 63655 (Marquand) to 30 in 63645 (Fredericktown).

Educational attainment ranges from 8.7% bachelor's+ in 63655 (Marquand) to 17.5% in 63645 (Fredericktown) — the breadth of educational profiles across the area.

Within Missouri, this is the #71 most populous of 116 counties and ranks #74 for median household income .

Weighted by population, the typical household earns about $55,582 across the county — reflecting what a typical resident sees, not a simple ZIP average.

16.3% of adults age 25+ hold a bachelor's degree or higher (1,489 of 9,132 reporting).

2 Standard delivery, 0 PO Box only, 0 single-entity Unique ZIPs serve this county.

Stories about Madison County


Big & sparse

A frontier county — vast land area with only a few residents per square mile. Daily life looks very different here than in the country's denser counties.

Total area
532
square miles
Avg density
24.8
people per sq mi
Population
13,193
across 2 ZIPs
Fredericktown
379.1 sq mi
11,554 residents
Marquand
152.5 sq mi
1,639 residents

Single-ZIP anchor

One ZIP holds the majority of this county's population — a sign of a county built around a single city or town.

Fredericktown

All ZIP Codes in Madison County


ZIPCityTypePopulationMedian IncomeArea (sq mi)10-yr Growth
63645FredericktownStandard11,554$54,747379.11.5%
63655MarquandStandard1,639$61,469152.56.8%

Adjacent & Nearby Counties